Which topical NSAID is FDA approved for the treatment of allergic conjunctivitis?

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Ketorolac is the topical NSAID that is FDA approved specifically for the treatment of allergic conjunctivitis. It works by inhibiting cyclooxygenase (COX), leading to a decrease in the production of prostaglandins, which are responsible for causing inflammation, pain, and other symptoms associated with allergic reactions. By alleviating these symptoms, ketorolac effectively provides relief for patients suffering from allergic conjunctivitis.

This approval is significant since it indicates the drug's suitability and effectiveness for this specific condition, which is characterized by itchy, red, and watery eyes due to allergens. Other NSAIDs like bromfenac, nepafenac, and flurbiprofen are primarily indicated for other purposes, such as postoperative inflammation or pain relief after cataract surgery, rather than for the direct treatment of allergic conjunctivitis.

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