Which of the following is NOT associated with corticosteroid use?

The option that is not associated with corticosteroid use is Bull's eye maculopathy. Bull's eye maculopathy, characterized by a specific pattern of retinal degeneration, is primarily associated with the use of chloroquine and hydroxychloroquine, which are medications used to treat malaria and certain autoimmune diseases. Corticosteroids, on the other hand, do not cause this type of maculopathy.

Corticosteroids are known to lead to several ocular side effects, including central serous chorioretinopathy (CSCR), which is associated with altered fluid dynamics in the retina and can be exacerbated by stress or steroids. Elevated intraocular pressure (IOP) is a well-documented consequence of corticosteroid therapy, as steroids can increase aqueous humor production and decrease outflow facility, leading to glaucoma in susceptible individuals. Additionally, corticosteroids are known to cause an increased risk of viral infections, such as herpes simplex due to their immunosuppressive effects, which can allow for reactivation of latent infections.

Thus, while corticosteroids carry the risk of CSCR, elevated IOP, and increased susceptibility to herpes infections, Bull's eye maculopathy distinctly associates with different pharmacological agents and is not a known effect of corticosteroid