Which of the following is a characteristic of topical corticosteroids used in ocular therapy?

Topical corticosteroids are commonly used in ocular therapy for their potent anti-inflammatory effects. One significant characteristic of these medications is their potential to elevate intraocular pressure (IOP). This is particularly important in patients who may be at risk for glaucoma or those with a history of elevated IOP. The mechanism behind this effect may involve the corticosteroids' influence on the trabecular meshwork and aqueous humor dynamics.

Elevated IOP can occur as a side effect because corticosteroids reduce the outflow of aqueous humor in the eye, leading to increased pressure. Monitoring IOP is crucial in patients receiving prolonged corticosteroid therapy, as it may necessitate additional treatment or closer observation. This aspect highlights the importance of understanding the systemic effects of therapies used for ocular conditions and the need for regular assessments during treatment.

The other characteristics listed, such as enhancing tear production or having a prolonged effect post-application, do not accurately represent the typical pharmacological profile of topical corticosteroids. Additionally, while corticosteroids can have a low side-effect profile when used short-term or as directed, their risk of raising IOP is a notable concern that requires attention in clinical practice.