Which of the following is NOT a known side effect of Pilocarpine?

Pilocarpine, a muscarinic antagonist used primarily in the treatment of glaucoma, has several known side effects primarily due to its action on the ciliary muscle and the iris sphincter. When pilocarpine is administered, it causes miosis (constriction of the pupil) and can result in browaches due to the increased tension in the ciliary muscle. This muscle contraction can also contribute to headaches, which are commonly reported by users of the medication.

Additionally, pilocarpine can induce a myopic shift, where the eye's focusing power is increased in the near direction, often experienced in patients as they become more myopic in their vision temporarily.

In contrast, a hyperopic shift refers to a situation where the eye’s focusing ability decreases for near vision, leading to an increased tendency towards farsightedness. Pilocarpine does not typically induce a hyperopic shift; rather, it generally results in a minor increase in myopia due to its pharmacological effects on ciliary muscle. Therefore, hyperopic shift is not associated with pilocarpine's known side effects, making it the correct choice in this question.