Which of the following is NOT a contraindication for a patient taking topical ophthalmic prostaglandins?

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Topical ophthalmic prostaglandins are commonly used to lower intraocular pressure in conditions like glaucoma. When considering contraindications for their use, it is important to understand the specific concerns related to each option provided.

Patients at risk for cystoid macular edema (CME) following cataract surgery, uveitis patients, and those with a history of herpes simplex keratitis represent groups where caution is warranted due to potential exacerbation of their conditions or complications. For instance, prostaglandins can influence inflammation and may lead to increased risks in patients who have recently undergone cataract surgery or have active uveitis. In the case of herpes simplex keratitis, these medications can indirectly encourage viral reactivation or lead to complications in patients predisposed to corneal epithelial issues.

Conversely, chronic obstructive pulmonary disease (COPD) is generally not recognized as a contraindication for the use of topical ocular prostaglandins. While systemic absorption is a consideration with any topical medication, the ocular administration of prostaglandins does not present specific risks or contraindications for patients with COPD. Therefore, these patients can typically be treated with topical prostaglandins without additional respiratory concerns, making this selection the one that is not a contraindication.

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