Which of the following conditions is NOT treated by topical adrenergic agonist medications?

Topical adrenergic agonists are used in various eye conditions primarily due to their ability to cause vasoconstriction, decrease intraocular pressure, and stimulate certain receptors that lead to therapeutic effects.

In acute glaucoma, these medications can help reduce intraocular pressure by facilitating aqueous humor outflow or decreasing its production. They are also useful in treating allergic conjunctivitis by providing symptomatic relief through vasoconstriction, which reduces redness and swelling in the conjunctiva.

Horner's syndrome can be diagnosed using topical adrenergic agonists. When applied, these agents can cause dilation of the pupil on the affected side if the postganglionic neuron is intact, helping confirm the diagnosis.

However, chronic dry eye is not treated effectively with topical adrenergic agonists. Conditions like dry eye involve issues with tear production or tear film stability, and adrenergic agonists do not address these underlying problems. Instead, the management of chronic dry eye typically involves lubricating eye drops or ointments, anti-inflammatory medications, and other approaches that directly focus on increasing tear production or enhancing ocular surface health.