What are the two main topical ophthalmic examples of CAIs that can be used for glaucoma treatment?

The correct answer identifies Brinzolamide and Dorzolamide as the two main topical ophthalmic carbonic anhydrase inhibitors (CAIs) used in the treatment of glaucoma. Both of these medications work by decreasing the production of aqueous humor, which helps to lower intraocular pressure that can lead to glaucoma.

Brinzolamide and Dorzolamide are specifically formulated for topical application, allowing direct delivery to the eye, which enhances their effectiveness and minimizes systemic side effects. These medications are often chosen for patients who may not tolerate beta-blockers or who require adjunctive therapy for better intraocular pressure control. Their mechanism of action as CAIs differentiates them from the other medications listed in the choices provided.

Understanding these specific CAIs is crucial for anyone practicing in ocular pharmacotherapy, as they represent an important class of medications for managing glaucoma.