Methylene blue has similar staining properties to Rose Bengal, except it also stains corneal what?

Methylene blue is known for its effective staining properties, particularly in visualizing certain structures in the eye. It is utilized in a variety of ocular applications primarily due to its ability to stain cellular components. While Rose Bengal is well-recognized for highlighting devitalized or damaged epithelial cells on the cornea, methylene blue serves a broader purpose.

One notable aspect of methylene blue is its affinity for nervous tissue. This characteristic makes it effective in demonstrating corneal nerves, which are often not visible under standard examination conditions. The ability of methylene blue to stain corneal nerves is particularly valuable in clinical settings as it can help in identifying issues related to corneal sensation, thus aiding in diagnosing conditions such as neurotrophic keratitis.

Understanding this feature of methylene blue supports its role in ocular pharmacology, as it enhances the visualization of the corneal architecture, including neuronal structures, providing essential information about corneal health and function.